科研人员
国内外学术任职:Genomics, Proteomics & Bioinformatics编委会成员
博士:武汉大学,1999
硕士:兰州大学,1996
学士:河北大学,1993
Email: dkniu@bnu.edu.cn
个人主页: http://cmb.bnu.edu.cn/teachers/niudk.htm
办公电话:010-58802064
主要讲授课程:生命科学导论、基因组学、生物科学史讲座
主要研究内容:细胞器基因组向细胞核的转移、基因组大小和GC含量的进化、内含子的起源与进化
近五年发表的主要论文:
1. Ma M.Y., Lan X.R. & Niu D.K. (2016) Intron gain by tandem genomic duplication: a novel case in a potato gene encoding RNA-dependent RNA polymerase. PeerJ 4: e2272.
2. Ma M.Y., Che X.R., Porceddu A. and Niu D.K. (2015) Evaluation of the mechanisms of intron loss and gain in the social amoebae Dictyostelium. BMC Evolutionary Biology 15: 286.
3. Ma M.Y., Zhu T., Li X.N., Lan X.R., Liu H.Y., Yang Y.F. & Niu DK (2015) Imprecise intron losses are less frequent than precise intron losses but are not rare in plants. Biology Direct 10: 24.
4. Jiang L., Li X.N. & Niu D.K. (2014) Higher frequency of intron loss from the promoter proximally paused genes of Drosophila melanogaster: Evidence consistent with delays in intron splicing as a selective force. Fly 8: 120-125.
5. Yang Y.F., Zhu T & Niu D.K. (2013) Association of intron loss with high mutation rate in Arabidopsis: Implications for genome size evolution. Genome Biology and Evolution 5: 723-733.
6. Zhu T. & Niu D.K. (2013) Mechanisms of intron loss and gain in the fission yeast Schizosaccharomyces. PLoS ONE 8: e61683.
7. Zhu T. & Niu D.K. (2013) Frequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron loss. BMC Biology 11: 23.
8. Niu D.K. & Jiang L. (2013) Can ENCODE tell us how much junk DNA we carry in our genome? Biochemical and Biophysical Research Communications 430: 1340-1343.
近五年主持的主要科研项目:
1、 国家自然科学基金面上项目(项目号:31671321):从受体的角度研究细胞器基因向细胞核基因组转移的机制,(2017.9-2020.12;60万元);
2、北京师范大学自主科研基金项目(项目号:2014KJJCB18):真核生物编码蛋白质基因内部结构进化,(2014.9-2017.8;35万元);
3、国家自然科学基金面上项目(项目号:31371283):基因组大小与内含子进化的比较研究,(2014.1-2017.12;80万元);
4、国家自然科学基金面上项目(项目号:31071112):近缘物种间和物种内内含子数目变异的进化机制,(2011.1-2013.12;35万元)。